| 翻訳と辞書 |
| Sodium lauroyl sarcosinate ： ウィキペディア英語版 |
Sodium lauroyl sarcosinate
| Section2 =
}}
Sodium lauroyl sarcosinate (INCI), also known as sarkosyl, is an ionic surfactant derived from sarcosine used as a foaming and cleansing agent in shampoo, shaving foam, toothpaste, and foam wash products. In molecular biology experiments, sarkosyl is used to inhibit the initiation of DNA transcription.
This surfactant is amphiphilic due to the hydrophobic 12-carbon chain (lauroyl) and the hydrophilic carboxylate. Since the nitrogen atom is in an amide linkage, the nitrogen is not pH active and is neutrally charged in all aqueous solutions regardless of pH. The carboxylate has a pKa of about 3.6 and is therefore negatively charged in solutions of pH greater than about 5.5.
pH-sensitive vesicles can be prepared using this surfactant with another cationic or water-insoluble amphiphiles such as 1-decanol.
Addition of an mixture of equal parts of sodium lauroyl sarcosinate and the non-ionic surfactant sorbitan monolaurate (S20) to water led to the formation of micelle-like aggregates, even though neither surfactant formed micelles when present alone. Such aggregates can help carry other small molecules, such as drugs, through the skin.
==In culture==
Sodium lauroyl sarcosinate was sold as a special ingredient called 'Gardol' in Colgate Dental Cream (toothpaste) during the 1950s〔(Do you remember Gardol? by Olga Werby, May 7, 2013 )〕〔(1956 Colgate Toothpaste with Gardol Original Advertisement )〕〔(Colgate Dental Cream Gardol Father Kids On Sled 1959 Antique Advertisement )〕
through the mid-1960s in the US〔(Colgate Dental Cream with Gardol advertisement in Life Magazine, May 29, 1963 page 4. )〕〔("Clinical Test Confirms Colgate a Leader in Reducing New Cavities! Read what happened when Colgate with Gardol was clinically tested against the most widely accepted fluoride dentifrice." ''Ebony'', June 1963, Vol. 18, No. 8, Colgate with Gardol ad )〕
and the mid-1970s in France.〔(Colgate Dental Cream with Gardol advertisement in a TV spot, November 17, 1975. )〕
Current use as a preventive dentifrice is in Arm & Hammer toothpaste.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
■ウィキペディアで「Sodium lauroyl sarcosinate」の詳細全文を読む
スポンサード リンク
| 翻訳と辞書 : 翻訳のためのインターネットリソース |
Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.
|
|